Safety and efficacy of very high-power short-duration ablation for pulmonary vein isolation

Abstract Funding Acknowledgements Type of funding sources: None. Background A very high-power short-duration (vHPSD) strategy radiofrequency (RF) ablation aims to minimize conductive heating and increase resistive heating. Purpose The aim our study is evaluate the feasibility, efficacy safety vHPSD for pulmonary vein (PV) isolation in patients presenting with paroxysmal or persistent atrial fibrillation (AF). Methods This prospective non-randomized enrolled consecutive AF undergoing PV isolation. was performed QDOT catheter, applying 90 W, 4 s, an irrigation 8 ml/min. RF delivered targeting interlesion distance ≤ 6 mm. PVI assessed at end encirclement Pentaray catheter by entrance block remapping. Results Overall 163 (29 AF) were enrolled. mean age 61±8 years, 60% had hypertension 10% diabetes mellitus. obtained all first-pass 144 (88%) a number 83±15 pulses. procedural time 85±26 min, fluoroscopy 9±6 min 5,5±1 min. In 5 (3%) access-related vascular complications occurred. follow-up (fu) 8±3 months (fu³6 109 patients; fu³12 15 patients) freedom from recurrence 97% overall population subgroups as well (Figure 1). Conclusions represents effective safe achieve patients.